Crossover Redefreiheit

مطالعات مورد – همگذری (Case Crossover Studies)

سخن سردبیر Editorial مجله دانشگاه علوم پزشکی رفسنجان دوره هجدهم، شهریور 1398، 513-514     مطالعات مورد – همگذری (Case Crossover Studies)   محسن رضائیان[1]   M. Rezaeian   مطالعات مورد - همگذری (Case Crossover Studies) به ویژه برای مشخص کردن تأثیر زودگذر مواجهه بر روی رخداد یک بیماری حاد، مناسب است. در این طراحی، به جای آن‌که یک گروه مجزا برای کنترل انتخاب  شود، هر مورد در نقش کنترل ...

Crossover interference

What is crossover interference? During prophase of meiosis in most eukaryotes, DNA recombination events between homologous chromosomes are induced to occur at high frequency, so there are usually multiple events per chromosome pair per meiosis. Whereas many of these recombination events are non-reciprocal, a subset results in reciprocal exchange of genetic material between chromosomes — crossov...

Meiotic recombination protein Rec12: functional conservation, crossover homeostasis and early crossover/non-crossover decision

In fission yeast and other eukaryotes, Rec12 (Spo11) is thought to catalyze the formation of dsDNA breaks (DSBs) that initiate homologous recombination in meiosis. Rec12 is orthologous to the catalytic subunit of topoisomerase VI (Top6A). Guided by the crystal structure of Top6A, we engineered the rec12 locus to encode Rec12 proteins each with a single amino acid substitution in a conserved res...

Weakest Crossover

Crossover sexual